The weight loss drugs Ozempic and Wegovy are wildly popular right now but what are the side effects when it comes to your bones and muscles? US Center for Sports Medicine, Orthepedic Surgeon Rick Lehman says that these drugs are relatively new, and their long-term effects are not fully understood. Dr. Lehman points out that while these medications are popular for weight loss, they often lead to a reduction in muscle mass rather than just fat, potentially increasing the percentage of body fat despite a lower overall weight. This could lead to a paradox where individuals are thinner but have a higher body fat percentage.